(Visited 66 times, 1 visits today)FacebookTwitterPinterestSave分享0 Here’s a list of news reports about stem cells for those interested in either health or bioethics.Stem cell research continues to promise amazing treatments, yet the use of human embryos is ethically troublesome. Adult stem cells and induced pluripotent stem cells (iPSC) offer ethical workarounds for embryonic stem cells in most cases. Here’s what’s developing on the stem cell front.Researchers take broad look at stem cells (Science Daily). “Sanford Research scientists recently published a review article in an issue of Stem Cells Translational Medicine focused on the study of and utility of adult-derived stem cells.” A new clinical trial opened for patients with rotator-cuff tears, using their own stem cells.Clonal reversal of ageing-associated stem cell lineage bias via a pluripotent intermediate (Nature Scientific Reports). This study looks at the potential for reversing aging with iPSCs treated to heal hematopoietic stem cells in the blood.The stem cell dynamics of wound healing (Medical Xpress). Researchers in Brussels are using mouse models to study how the body’s stem cells work to repair tissues in the skin. The research has been published in Nature Communications. See also Science Daily.Autophagy maintains the metabolism and function of young and old stem cells (Nature). How does the body keep its stem cells healthy over a lifetime? “Our results demonstrate that autophagy actively suppresses haematopoietic stem-cell metabolism by clearing active, healthy mitochondria to maintain quiescence and stemness, and becomes increasingly necessary with age to preserve the regenerative capacity of old haematopoietic stem cells.”Stem cells derived neuronal networks grown on a chip as an alternative to animal testing (Science Daily). Scientists at the University of Bern are experimenting with stem cells assays in “multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins.” This method “could serve in minimizing animal experiments as well as provide a physiological relevant platform for drug-screening of neuroactive compounds.”Findings reveal effect of embryonic neural stem cell development on later nerve regeneration capacity (Medical Xpress).The cells responsible for neurogenesis in the mature brain are called adult neural stem cells, but little is known about their developmental origins. Now an international research collaboration led by Magdalena Götz, Professor of Physiological Genomics at LMU’s Biomedical Center and Director of the Institute for Stem Cell Research at the Helmholtz Zentrum Munich, has demonstrated that the mode of division of stem cells has a profound influence on the numbers of adult neural stem cells formed during embryonic development.Scientists wage fight against aging bone marrow stem cell niche (Science Daily). Scientists at Cincinnati Hospital are also looking at hematopoietic stem cells and how they age. Trouble is, the bone marrow also ages with the HSCs. These scientists “propose rejuvenating the bone marrow niche where HSCs are created.”DNA repair and replication links to pluripotency and differentiation capacity of pig iPS cells (PLoS One). This paper looks into whether iPSCs derived from pig cells are stable enough to be used in human treatments.Bioethics and Genome EditingScientists create artificial mouse ’embryo’ from stem cells for first time (Science Daily). Studying how mouse embryos develop is OK, but if mad scientists start creating human embryos from stem cells some day, it won’t matter if they came from adult stem cells or iPSCs. It will still be morally wrong. These scientists are looking for workarounds to the shortage of human embryos to play with, and the 13-day rule for destroying them.Bioethics: Democracy in vitro (Nature). In this Book Review, “Insoo Hyun weighs up a treatise exploring the ethical deliberations surrounding embryo research.” The book is Experiments in Democracy: Human Embryo Research and the Politics of Bioethics, by J. Benjamin Hurlbut (Columbia University Press: 2017).US science advisers outline path to genetically modified babies (Nature). This related bioethics story should sound alarms. “Modified human embryos should be allowed if researchers meet strict criteria, says long-awaited National Academies report.”Safe and ethical ways to edit the human genome (The Conversation). Rosa Castro gives 10 guidelines for avoiding the ethical qualms about a brave new world of “designer babies.”First results of CRISPR gene editing of normal embryos released (New Scientist). It’s coming. The Chinese have already started. Is the world ready for direct editing of the human genome? Can ethics keep up with the technology? This liberal news service doesn’t seem overly concerned about it. It’s a way to cure deadly genetic diseases; isn’t that a moral thing? It always starts out that way, but eugenics waits in the wings. What happens to those born with the genetic disease? How will they be treated? Read about other issues, such as “mosaicism” – editing that doesn’t fix all the bugs.
An assistant sub-inspector of the Border Security Force (BSF) and his wife have been declared “foreigners” by a Foreigners’ Tribunal in eastern Assam’s Jorhat town.The tribunal declared Muzibur Rahman and his wife as non-Indians in an ex parte or one-sided judgement in July.The citizenship of the officer’s parents and his siblings are, however, not in doubt. The family is based in Golaghat district’s Udaypur-Mikirpatty close to the Assam-Nagaland border.Mr. Rahman, currently posted in Punjab, came to know of the judgement against him when he came home on leave in July last week.He said the Assam police’s border wing had relied on a ‘drunkard’s account’ to submit a report to the tribunal against him.The border wing, established in 1962 to initially prevent infiltration of Pakistanis, is tasked with detection and deportation of foreigners. Currently, 100 Foreigners’ Tribunals decide the fate of such “foreigners” referred by this wing.“We have land documents of 1923. It is a pity that a genuine Indian citizen has been made a foreigner on the basis of a drunkard’s feedback. My family did not receive the tribunal’s notice. The chief of our village also did not inform me when I was away on duty,” Mr. Rahman said, adding that he had approached the Gauhati High Court.In June, the court gave bail to retired soldier Mohammed Sanaullah who, was on May 28, was declared a foreigner by a Foreigners’ Tribunal in Guwahati. He had spent more than a week in a detention camp in western Assam’s Goalpara.
India won the toss and elected to field first against EnglandWelcome to the coverage of the 5th ODI between India and England from the Headingley cricket ground in Leeds.Scorecard | Match Photos Team India were bowled for 253 runs while chasing an imposing total of 294 runs against England in the 5th ODI at Headingley.The players exchange pleasantries. England finally got their act together to prevent India from sweeping the series. After Root’s ton powered them to a fine total, the English bowlers removed Rahane and Kohli cheaply. Dhawan threatened for a brief while before he was undone by Moeen Ali. The English intensity though nosedived as they dropped a couple of catches. Rayudu got to his fifty but threw it away, instead of setting up an edifice for the force multipliers. Raina had an off-day and so did Dhoni. Meanwhile, Jaddu walloped the hosts all around the park. All it did though was to reduce the margin of defeat. Jimmy and Co. put up a much improved performance. Barring Woakes and Tredwell, all others contributed. Stokes followed up his cameo with the bat with 3 wickets, vindicating his recall. In hindsight, the series could have been more interesting had England engineered such a performance a game or two ago. England have FINALLY clinched a MUCH-NEEDED WIN against India in the series!!48.4 overs: That’s OUT!! Steven Finn has bowled Ravindra Jadeja on a fuller delivery. Jadeja was looking to cut and chops it back onto the stumps. Ravindra Jadeja’s fighting innings come to an end at 87 runs off 68 balls with nine boundaries and two sixes.advertisement48.3 overs: FOUR!! Ravindra Jadeja back away and tonks it over the in-field for another boundary. This is turning out to be a GEM OF AN INNINGS from Jadeja!!48.2 overs: FOUR!! Ravindra Jadeja makes room and whacks it past mid-off for a boundary. With Umesh Yadav(0) and Ravindra Jadeja(79) at the crease, India currently require 51 runs off 12 balls with three wickets in hand.FIVE RUNS off the over!!47.5 overs: FOUR!! Ravindra Jadeja picks the slower delivery and flicks it towards deep square leg for a boundary. FIFTEEN RUNS off the over!!46.5 overs: FOUR!! Ravindra Jadeja makes room and drills it through extra cover for the third boundary in the over. Jadeja is ON FIRE here!!46.2 overs: FOUR!! Ravindra Jadeja takes it on the full and scoops it towards fine leg for another boundary. BACK-TO-BACK BOUNDARIES for India!!46.1 overs: FOUR!! Ravindra Jadeja leans forward and whacks it through covers for a boundary. FIFTEEN RUNS off the over!!45.4 overs: SIX!! Ravindra Jadeja makes room and smashes it deep into the stands over the cow corner for another maximum. Jadeja is TURNING IT ON for India!!Sir Jadeja UNVEILS HIS SWORD to celebrate his FIGHTING HALF-CENTURY!!45.2 overs: SIX!! Ravindra Jadeja stands tall and smashes it back into the stands for the maximum. That’s FIFTY for Jadeja!!TWO RUNS off the over!!Umesh Yadav comes to the crease for India.44.4 overs: OUT!! Ben Stokes has got Mohammed Shami out caught at extra cover. Shami takes it on the full and slices it straight into the hands of Alex Hales for a simple catch. Mohammed Shami departs for a duck.Mohammed Shami comes to the crease for India.44.1 overs: That’s OUT!! Bhuvneshwar Kumar has run-out by Steven Finn while trying to sneak in a second run. Ravindra Jadeja punches the ball through midwicket and calls for two straightaway while Steven Finn covers ground quickly to fire in a throw to catch Kumar short at the crease. Bhuvneshwar Kumar departs after scoring one run off three balls. With Bhuvneshwar Kumar(6) and Ravindra Jadeja(36) at the crease, India currently require 90 runs off 42 balls with three wickets in hand.FIVE RUNS off the over!!Bhuvneshwar Kumar comes to the crease for India.England are CRUISING towards a HIGHLY-AWAITED WIN here!!42.5 overs: OUT!! Ben Stokes has got Ravichandran Ashwin out caught at covers. Ashwin was looking for the big shot but gets a top-edge that goes straight down the throat of Steven Finn who doesn’t drop those. Ravichandran Ashwin departs after scoring 16 runs off 19 balls with a boundary. Another BLOW for India!!SEVEN RUNS off the over!!41.3 overs: FOUR!! Ravichandran Ashwin picks the slower ball and smacks it towards deep cover for a boundary. A MUCH-NEEDED BOUNDARY for India!! With Ravichandran Ashwin(6) and Ravindra Jadeja(33) at the crease, India are currently at 187/6 after 40 overs.FOUR RUNS off the over!!Ravichandran Ashwin comes to the crease for India.36.5 overs: That’s OUT!! Steven Finn has got MS Dhoni out caught at covers. Dhoni reaches out and slices it straight in the hands of Ben Stokes who takes an easy catch. MS Dhoni departs after scoring 29 runs off 42 balls with a boundary and a six. BIG BLOW for India!! advertisementWith MS Dhoni(4) and Ambati Rayudu(35) at the crease, India are currently at 102/4 after 26 overs.SIX RUNS off the over!!25.1 overs: FOUR!! Ambati Rayudu goes on the backfoot and flays the late cut behind point for a boundary. Rayudu NEEDS TO CARRY ON from here!! With MS Dhoni(0) and Ambati Rayudu(28) at the crease, India are currently at 91/4 after 22 overs.Moeen Ali has been the find of this tour for England. Hope ECB doesn’t treat him like KP later #IndvsEng Abhishek (@ImAbhishek_) September 5, 2014ONE RUN off the over!!MS Dhoni comes to the crease for India.21.4 overs: OUT!! Moeen Ali has got Suresh Raina out caught by the wicket-keeper. Raina rocks back and flays the cut only to get an outside edge through to Jos Buttler behind the stumps. Suresh Raina departs after scoring 18 runs off 23 balls with two boundaries. BIG WICKET for England!! With Suresh Raina(18) and Ambati Rayudu(27) at the crease, India are currently at 90/3 after 21 overs.TEN RUNS off the over!!20.3 overs: FOUR!! Ambati Rayudu gets a big stride forward and hammers it over midwicket for a boundary. Rayudu gets a MOVE ON here!!20.1 overs: FOUR!! Suresh Raina uses his feet and hoicks it over covers for a boundary. A WARM WELCOME from Raina!!James Tredwell comes into the attack for England. With Suresh Raina(13) and Ambati Rayudu(22) at the crease, India are currently at 80/3 after 20 overs.TEN RUNS off the over!!19.6 overs: SIX!! Ambati Rayudu skips down the track and sends it back over the bowler’s head for the maximum. TERRIFIC HIT from Rayudu!! With Suresh Raina(11) and Ambati Rayudu(14) at the crease, India are currently at 70/3 after 19 overs.EIGHT RUNS off the over!! 18.1 overs: FOUR!! Suresh Raina leans into the drive and sends it scurrying through covers for a boundary. That was MARVELLOUS from Raina!! With Suresh Raina(4) and Ambati Rayudu(9) at the crease, India are currently at 58/3 after 17 overs.2 dropped catches in the same over, Raina and Rayudu just got an extra life. Plz make the most of it ? #IndvsEng Need to win the series 4-0 Aditya Anil (@Aditya69577) September 5, 2014TWO RUNS off the over!!Looks like England are TRYING TO EMULATE India’s fielding during the Tests!!14.6 overs: CATCH-DROPPED!! Alastair Cook has dropped Suresh Raina at first slip. Raina goes for the drive and gets an outside edge through to Cook who dives to his left but fails to grab it in the end. This is POOR FIELDING from England!!14.4 overs: CATCH-DROPPED!! Chris Woakes has dropped Ambati Rayudu at long-on. Rayudu was looking for the big shot but gets a top-edge high in air while Woakes covers ground quickly only to spill a crucial chance. That’s GOING TO HURT England!! With Suresh Raina(0) and Ambati Rayudu(4) at the crease, India are currently at 49/3 after 14 overs.advertisementSIX RUNS off the over!!Suresh Raina comes to the crease for India.13.6 overs: That’s OUT!! Moeen Ali has bowled Shikhar Dhawan on a slower delivery. Dhawan was looking to flays the slog sweep again but gets beaten in the air as the ball makes a mess of the stumps. Shikhar Dhawan departs after scoring 31 runs off 44 balls with four boundaries and a six. India IN A SPOT OF BOTHER now!!13.3 overs: SIX!! Shikhar Dhawan bends down and hammers it over deep midwicket fence for the maximum. That was SMASHED WITH BRUTAL FORCE by Dhawan!! Steven Finn comes into the attack for England. With Shikhar Dhawan(24) and Ambati Rayudu(3) at the crease, India are currently at 41/2 after 12 [email protected] is just missing his bestie @StuartBroad8 here in this series #IndvsEng #BowlingDuo Achal Sharma (@achalsharma17) September 5, 2014TWO RUNS off the over!! First sign of spin, Moeen Ali comes into the attack for England. With Shikhar Dhawan(22) and Ambati Rayudu(1) at the crease, India are currently at 37/2 after 10 overs.EIGHT RUNS off the over!!9.6 overs: FOUR!! Shikhar Dhawan gets on the frontfoot and drills it straight down the ground for another boundary. That was Dhawan AT HIS BEST!!9.3 overs: FOUR!! Shikhar Dhawan hangs back and crashes the cut past point for a blazing boundary. That was FIERCELY STRUCK by Dhawan!! With Shikhar Dhawan(11) and Ambati Rayudu(0) at the crease, India are currently at 25/2 after seven overs.EXCELLENT OVER by Anderson, a CRUCIAL WICKET and just one run off it!!Kohli has become anderson’s bunny ? #IndvsEng Sneha (@iSneha32) September 5, 2014Ambati Rayudu comes to the crease for India.6.6 overs: OUT!! James Anderson has got Virat Kohli out caught at first slip. Kohli was looking to defend but gets an outside edge through to Alastair Cook who takes a good diving catch. Virat Kohli departs after scoring 13 runs off 21 balls with two boundaries. Kohli’s DISMAL SHOW continues for India!! With Shikhar Dhawan(10) and Virat Kohli(13) at the crease, India are currently at 24/1 after six overs.SIX RUNS off the over!! @imVkohli showing the same intensity and aggressiveness which was missing throughout the series. #EngvInd #IndvsEng Shahan Sibtain (@Sibtain1314) September 5, 20145.2 overs: FOUR!! Virat Kohli hangs back and clips it towards fine leg for a boundary. POOR LINE from Woakes!! With Shikhar Dhawan(10) and Virat Kohli(7) at the crease, India are currently at 18/1 after five overs.NINE RUNS off the over!! Perfect Platform For Kohli… ?? #IndvsEng Waiting For Big One.. Come On Cheeku.. ? Er. Balu (VIP) (@BaluMahe) September 5, 20144.4 overs: FOUR!! Shikhar Dhawan waits for it and flicks it towards deep midwicket fence for a boundary. 4.2 overs: FOUR!! Virat Kohli leans forward and flicks it through midwicket for a boundary. POOR LINE from Anderson!! With Shikhar Dhawan(6) and Virat Kohli(2) at the crease, India are currently at 9/1 after three overs.SIX RUNS off the over!!1.4 overs: FOUR!! Shikhar Dhawan leans forward and slices it behind point for the first boundary in the innings. That was UNLUCKY for Woakes!!Chris Woakes will bowl from the other end for England.ONE RUN off the over!!Virat Kohli comes to the crease for India.0.3 overs: That’s OUT!! James Anderson has got Ajinkya Rahane out caught at point. Rahane reaches out and slices it straight into the hands of Eoin Morgan who takes a comfortable catch. Ajinkya Rahane departs for a golden duck. EARLY BLOW for India!!Shikhar Dhawan and Ajinkya Rahane are out in the middle for India while James Anderson will start the proceedings for England. England scored 294 runs at the loss odf seven wickets after batting first against India at Headlingley. India made early inroads, reducing the hosts to 39-2. Cook essayed some gorgeous drives and put the innings back on track along with the busy Joe Root. The English captain went for one sweep too many and top-edged one with Dhoni taking a loopy catch. Just when it seemed like Ashwin and Jaddu were in their groove, Buttler and Root brought out the axe and daggers to smash 55 runs in the Batting PP. Root perished soon after reaching three figures, but Stokes took over the baton to power England to a good total. Shami, who fired in the yorkers at the death, was the pick of the Indian bowlers. Experts reckon that the pitch won’t change much. Mark Nicholas on air said that it seems like a ‘Kohli Day’. Will it be Kohli’s day? Do join us back in a short while to find out. But before we head for a break, help yourself to part 46 of our series on India-England Tests in England.Highest totals for Eng in ODIs at Leeds 321/7 v SL, 2006 LOST 295/6 v NZ, 1990 LOST 294/7 v Ind Today Result??? #IndvsEng Bharath Seervi (@SeerviBharath) September 5, 2014That’s the END OF INNINGS for England!! ELEVEN RUNS off the over!!49.6 overs: Ben Stokes leans forward and drills it towards midwicket where the awkward bounce forces a misfield from the fielder as the ball races away to the fence. GREAT FINISH for England!! 49.3 overs: FOUR!! Ben Stokes shuffles across and scoops it towards fine leg for a boundary. Mohammed Shami will bowl the FINAL OVER for India!!With James Tredwell(6) and Ben Stokes(24) at the crease, England are currently at 283/7 after 49 overs.TWELVE RUNS off the over!!48.4 overs: SIX!! Ben Stokes bends down and smashes it over deep square leg for the maximum. Yadav is LEAKING CRUCIAL RUNS here!! With James Tredwell(5) and Ben Stokes(15) at the crease, England are currently at 271/7 after 48 overs.SIX RUNS off the over!!James Tredwell comes to the crease for England.47.3 overs: OUT!! Mohammed Shami has bowled Chris Woakes on a steaming yorker. Woakes was looking to make room for the big shot but misses it as the ball makes a mess of the stumps. Chris Woakes departs after scoring nine runs off nine balls with two boundaries. With Chris Woakes(9) and Ben Stokes(14) at the crease, England are currently at 265/6 after 47 overs.TWELVE RUNS off the over!!46.3 overs: FOUR!! Chris Woakes rocks back and crashes the cut behind backward point for a boundary. 46.1 overs: SIX!! Ben Stokes shimmies down the track and bludgeons it back over the bowler’s head for the maximum. That was TONKED by Stokes!!With Chris Woakes(4) and Ben Stokes(7) at the crease, England are currently at 253/6 after 46 overs.FIVE RUNS off the over!!Chris Woakes comes to the crease for England.45.2 overs: That’s OUT!! Mohammed Shami has got Joe Root out caught at short fine leg. Root shuffles across looking to scoop it over short fine leg but sends it straight into the hands of Ravichandran Ashwin who takes a good diving catch. Joe Root departs after scoring 113 runs off 108 balls with 10 boundaries and three sixes. BRILLIANT INNINGS from Root!!SEVENTEEN RUNS off the over!!44.6 overs: SIX!! Joe Root picks the length early and smokes it over long-off for the maximum. Root is ON A ROLL here!!44.5 overs: FOUR!! Joe Root flays the reverse-sweep and sends it towards third man for a boundary.44.4 overs: SIX!! Joe Root gets a big stride forward and smashes it over deep midwicket for the maximum. That’s 2nd ODI HUNDRED for Root!! With Joe Root(88) and Jos Buttler(46) at the crease, England are currently at 214/4 after 41 overs.EIGHT RUNS off the over!!40.6 overs: FOUR!! Joe Root picks the length early and smacks it towards deep midwicket for a boundary.NINE RUNS off the over!!39.1 overs: FOUR!! Joe Root gets to the pitch of the delivery and drills it through covers for a boundary.TWELVE RUNS off the over!!38.5 overs: SIX!! Joe Root bends down and flays the slog sweep for the maximum. That was STRUCK POWERFULLY by Root!!FOURTEEN RUNS off the over!!35.3 overs: SIX!! Jos Buttler crashes the cut and gets a top-edge over the third man fence for the maximum. That was SMOKED by Buttler!!35.2 overs: FOUR!! Jos Buttler makes room and thrashes it past mid-off for a boundary.That’s a WICKET MAIDEN from Ashwin!!Jos Buttler is the new man in for England.28.6 overs: OUT!! Ravichandran Ashwin has got Eoin Morgan out stumped by the wicket-keeper. Morgan was looking to use his feet but gets beaten with the spin as MS Dhoni whips the bails off in a flash to catch him short at the crease. Eoin Morgan departs after scoring 14 runs off 34 balls with a boundary.23.5 overs: FOUR!! Eoin Morgan flays the reverse-sweep and sends it racing past backward point for a boundary.THREE RUNS off the over!!Eoin Morgan comes to the crease for England.19.6 overs: That’s OUT!! Suresh Raina has got Alastair Cook out caught by the wicket-keeper. Cook was looking to sweep but gets a top-edge that goes high in the air as MS Dhoni completes a simple catch. Alastair Cook departs after scoring 46 runs off 64 balls with six boundaries. BIG BLOW for England!!14.5 overs: FOUR!! Joe Root employs the straight drive and sends it scurrying back past the bowler for a boundary. That was CLASSY from Root!!FIVE RUNS off the over!!Joe Root comes to the crease for England.6.6 overs: OUT!! Bhuvneshwar Kumar has got Moeen Ali out caught at third man. Ali reaches out for the wide delivery and slices it straight down the throat of Umesh Yadav who doesn’t drop those. Moeen Ali departs after scoring nine runs off eight balls with two boundaries. Another BLOW for England!!6.4 overs: FOUR!! Alastair Cook goes for the drive and gets an outside edge past the slip cordon for a boundary. That was UNLUCKY for Bhuvi!!FOUR RUNS off the over!!Moeen Ali comes to the crease for England.3.4 overs: That’s OUT!! Umesh Yadav has got Alex Hales out caught at midwicket. Hales was looking to pull it over midwicket but sends it straight in the hands of Ajinkya Rahane who takes it comfortably. Alex Hales departs after scoring four runs off nine balls. EARLY BLOW for England!!SIX RUNS off the over!!1.5 overs: FOUR!! Alastair Cook pokes at the length delivery and gets an outside edge past the slip cordon for a boundary. LUCKY ESCAPE for Cook!!Umesh Yadav will bowl from the other end for India.TEN RUNS off the over!!0.6 overs: FOUR!! Alastair Cook rocks back and employs the cut shot again for another boundary. Cook off to a POSITIVE START here!!0.4 overs: FOUR!! Alastair Cook goes on the backfoot and crashes the cut behind point for the first boundary in the innings. FAB SHOT from Cook!!Alastair Cook and Alex Hales are out in the middle for England while Bhuvneshwar Kumar will start the proceedings for India.TOSS: India won the toss and elected to field against England.Teams(from):India: Mahendra Singh Dhoni(c/wk), Shikhar Dhawan, Murali Vijay, Virat Kohli, Ajinkya Rahane, Suresh Raina, Ambati Rayudu, Stuart Binny, Sanju Samson, R Ashwin, Ravindra Jadeja, Karn Sharma, Mohit Sharma, Umesh Yadav, Mohammad Shami, Dhawal Kulkarni, Bhuvneshwar Kumar.England: Alastair Cook(c), Moeen Ali, James Anderson, Gary Ballance, Ian Bell, Jos Buttler(wk), Steven Finn, Harry Gurney, Alex Hales, Chris Jordan, Eoin Morgan, Joe Root, Ben Stokes, James Tredwell, Chris Woakes